Student Projects

To address this century-old problem, the Laboratory for Bone Biomechanics has established a novel approach termed “spatial mechanomics”. Spatial mechanomics is defined as the integration of spatially-resolved “omics” with in silico models of the mechanical environment to investigate the interactions between local mechanical environments and cellular / molecular responses (Figure 1). This is a highly cross-disciplinary area of research combining in vivo models, imaging, “omics” techniques, mechanical testing and computational modelling / analyses. There are opportunities for student projects within this area of research that can be tailored to suitable candidates. Ideally applicants will be candidates with an interest or experience in musculoskeletal research, “omics” techniques, computational analyses, mechanical engineering, histology and/or image processing.

We are interested in the following: • To develop a molecular-based understanding of bone healing mechanobiology. • To investigate how this mechano-sensitivity is compromised with age.

Please contact Neashan Mathavan via: nmathavan@ethz.ch Obs! Please include your CV and academic transcript (i.e. list of courses you have completed with grades) with any expression of interest in this project.